VarScan
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The advent of massively parallel sequencing technologies has fundamentally changed the study of genetics. New platforms like the Illumina GAIIx and the Roche GS yield unprecedented levels of sequencing throughput. The analysis and interpretation of data from next-generation sequencing platforms presents a substantial informatics challenge.
VarScan is a platform-independent, technology-independent software tool for identifying SNPs and indels in massively parallel sequencing of individual and pooled samples. Given data for a single sample, VarScan identifies and filters germline variants based on read counts, base quality, and allele frequencyh. Given data for a tumor-normal pair, VarScan also determines the somatic status of each variant (Germline, Somatic, or LOH) by comparing read counts between samples.
FEATURES:
· Calls SNPs and Indels from SAMtools pileup files
· Filters variants by coverage, read depth, variant frequency, and base quality
· Determines somatic status (Somatic, Germline, LOH) for Tumor-Normal pairs
· Compares, merges, and intersects two lists of variants
· Limits variant calls to a set of target positions or target regions
Free download from Shareware Connection - Variant detection in massively parallel sequencing data
Version: 2. 2. 2010 | Size: 82 KB | Platform: WinOther
Released Date: 22-05-2012 | Rating: 0 | Title: VarScan
Author Url: http://varscan.sourceforge.net/
Program Info Url: http://varscan.sourceforge.net/
Download Url: http://sourceforge.net/projects/varscan/files/VarScan.v2.2.10.jar/download
VarScan for Windows - VarScan is a platform-independent, technology-independent software tool for identifying SNPs and indels in massively parallel sequencing of individual and pooled samples.
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Shareware Connection periodically updates pricing and software information of 'VarScan' from company source 'Dan Koboldt' , so some information may be slightly out-of-date. You should confirm all information before relying on it. Software piracy is theft, Using 'VarScan' crack, password, serial numbers, registration codes, key generators is illegal and prevent future development of VarScan.
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