PlateKi
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The PlateKi application can be used in leading pharmaceutical research laboratories to determine &tight-binding&or &classical& inhibition constants from raw plate-reader data. Associated IC50 values are also determined for compatibility with most corporate databases.
Benefits:
- High processing speed (approximately 100 milliseconds per inhibition constant, including progress curve analysis).
- Outlier exclusion minimizes labor and removes subjective bias.
- Can be used for secondary in-vitro screening of purified enzymes, or in cell-based assays.
- Summary output file can be imported into Excel and/or corporate databases.
FEATURES:
· Automatic model selection in fitting the reaction progress curves (straight line, quadratic parabola, first or second degree exponential).
· Automatic initial estimate of the inhibition constant .
· Optional robust regression with automatic exclusion of outliers .
· Determination of nonsymmetrical confidence intervals for model parameters according to the profile-t method (Bates & Watts, 1988).
· Fitting of dose-response curves either to the Morrison equation for tight binding or to the four-parameter logistic equation.
Free download from Shareware Connection - Determination of inhibition constants and IC-50 from plate-reader data
Version: 4.07.048 | Size: 5325 KB | Platform: WinOther
Released Date: 05-06-2012 | Rating: 0 | Title: PlateKi
Author Url: http://www.biokin.com/
Program Info Url: http://www.biokin.com/
Download Url: http://www.biokin.com/download/files/plateki-install.zip
Screenshot Url: http://www.biokin.com/plateki/img/pki-data.jpg
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Shareware Connection periodically updates pricing and software information of 'PlateKi' from company source 'BioKin, Ltd.' , so some information may be slightly out-of-date. You should confirm all information before relying on it. Software piracy is theft, Using 'PlateKi' crack, password, serial numbers, registration codes, key generators is illegal and prevent future development of PlateKi.
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