IsoEM
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The IsoEM package can be used to infer isoform and gene expression levels from high-throughput transcriptome sequencing (RNA-Seq) data. IsoEM uses a novel expectation-maximization algorithm that exploits read disambiguation information provided by the distribution of insert sizes generated during sequencing library preparation, and takes advantage of base quality scores, strand, and read pairing information (if available). Empirical experiments on synthetic datasets show that the algorithm significantly outperforms existing methods of isoform and gene expression level estimation from RNA-Seq data, for details see our AMB paper.
Free download from Shareware Connection - The IsoEM package can be used to infer isoform and gene expression levels from high-throughput transcriptome sequencing (RNA-Seq) data.
Version: 1.0.6 | Size: 3409 KB | Platform: WinOther
Released Date: | Rating: 0 | Title: IsoEM
Author Url: http://dna.engr.uconn.edu
Program Info Url: http://dna.engr.uconn.edu
Download Url: http://dna.engr.uconn.edu/software/IsoEM/IsoEM-1.0.6.zip
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