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fastsimcoal

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While preserving all the simulation flexibility of simcoal2, fastsimcoal is now implemented under a faster continous-time sequential Markovian coalescent approximation, allowing it to efficiently generate genetic diversity for different types of markers along large genomic regions, for both present or ancient samples. It includes a parameter sampler allowing its integration into Bayesian or likelihood parameter estimation procedure.

fastsimcoal can handle very complex evolutionary scenarios including an arbitrary migration matrix between samples, historical events allowing for population resize, population fusion and fission, admixture events, changes in migration matrix, or changes in population growth rates. The time of sampling can be specified independently for each sample, allowing for serial sampling in the same or in different populations.

Different markers, such as DNA sequences, SNP, STR (microsatellite) or multi-locus allelic data can be generated under a variety of mutation models (e.g. finite- and infinite-site models for DNA sequences, stepwise or generalized stepwise mutation model for STRs data, infinite-allele model for standard multi-allelic data).

fastsimcoal can simulate data in genomic regions with arbitrary recombination rates, thus allowing for recombination hotspots of different intensities at any position. fastsimcoal implements a new approximation to the ancestral recombination graph in the form of sequential Markov coalescent allowing it to very quickly generate genetic diversity for >100 Mb genomic segments.

Free download from Shareware Connection - While preserving all the simulation flexibility of simcoal2

Publisher: Laurent Excoffier | License: Freeware | Price: 0.00
Version: 1.1.1 | Size: 1505 KB | Platform: WinOther
Released Date: | Rating: 0 | Title: fastsimcoal

Author Url: http://cmpg.unibe.ch
Program Info Url: http://cmpg.unibe.ch
Download Url: http://cmpg.unibe.ch/software/fastsimcoal/downloads/fsc_win32.zip

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Shareware Connection periodically updates pricing and software information of 'fastsimcoal' from company source 'Laurent Excoffier' , so some information may be slightly out-of-date. You should confirm all information before relying on it. Software piracy is theft,  Using 'fastsimcoal' crack, password, serial numbers, registration codes, key generators is illegal and prevent future development of fastsimcoal.

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