Software Listing of Author : "Biokin, Ltd."
- DynaFit 4.04.061 Beta
- License: Freeware
- Price: 0.00


The DynaFit application was developed to perform nonlinear least-squares regression of chemical kinetic, enzyme kinetic, or ligand-receptor binding data. The experimental data can be either initial reaction velocities in dependence on the concentration of varied species (e.g., inhibitor concentration vs. velocity), or the reaction progress curves (e.g., time vs. absorbance). The main advantage in using the program DynaFit is in the ability to characterize the (bio)chemical reacting system in terms of symbolic, or stoichiometric, equations. For example, the ``slow, tight'' inhibition of a dissociative dimeric enzyme is described by the following text: Monomer + Monomer Enzyme : k1 k2 Enzyme + Inhibitor Complex : k3 k4 Enzyme + Substrate ReactiveX : k5 k6 ReactiveX -- Product + Enzyme : k7 k8 The names of chemical species...
- Publisher: BioKin, Ltd.
- Date Released: 17-07-2012
- Download Size: 5939 KB
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- Platform: WinOther
- PlateKi
- License: Shareware
- Price:


The PlateKi application can be used in leading pharmaceutical research laboratories to determine &tight-binding&or &classical& inhibition constants from raw plate-reader data. Associated IC50 values are also determined for compatibility with most corporate databases. Benefits: - High processing speed (approximately 100 milliseconds per inhibition constant, including progress curve analysis). - Outlier exclusion minimizes labor and removes subjective bias. - Can be used for secondary in-vitro screening of purified enzymes, or in cell-based assays. - Summary output file can be imported into Excel and/or corporate databases. FEATURES: · Automatic model selection in fitting the reaction progress curves (straight line, quadratic parabola, first or second degree exponential). · Automatic initial estimate of the inhibition...
- Publisher: BioKin, Ltd.
- Date Released: 05-06-2012
- Download Size: 5325 KB
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- Platform: WinOther